Endothelial repair in stented arteries is accelerated by inhibition of Rho-associated protein kinase

AIMS: Stent deployment causes endothelial cells (EC) denudation, which promotes in-stent restenosis and thrombosis. Thus endothelial regrowth in stented arteries is an important therapeutic goal. Stent struts modify local hemodynamics, however the effects of flow perturbation on EC injury and repair...

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Detalles Bibliográficos
Autores principales: Hsiao, Sarah T., Spencer, Tim, Boldock, Luke, Prosseda, Svenja Dannewitz, Xanthis, Ioannis, Tovar-Lopez, Francesco J., Van Beusekom, Heleen M. M., Khamis, Ramzi Y, Foin, Nicolas, Bowden, Neil, Hussain, Adil, Rothman, Alex, Ridger, Victoria, Halliday, Ian, Perrault, Cecile, Gunn, Julian, Evans, Paul C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157135/
https://www.ncbi.nlm.nih.gov/pubmed/27671802
http://dx.doi.org/10.1093/cvr/cvw210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157135/
https://www.ncbi.nlm.nih.gov/pubmed/27671802
http://dx.doi.org/10.1093/cvr/cvw210

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