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Endothelial repair in stented arteries is accelerated by inhibition of Rho-associated protein kinase
AIMS: Stent deployment causes endothelial cells (EC) denudation, which promotes in-stent restenosis and thrombosis. Thus endothelial regrowth in stented arteries is an important therapeutic goal. Stent struts modify local hemodynamics, however the effects of flow perturbation on EC injury and repair...
Autores principales: | Hsiao, Sarah T., Spencer, Tim, Boldock, Luke, Prosseda, Svenja Dannewitz, Xanthis, Ioannis, Tovar-Lopez, Francesco J., Van Beusekom, Heleen M. M., Khamis, Ramzi Y, Foin, Nicolas, Bowden, Neil, Hussain, Adil, Rothman, Alex, Ridger, Victoria, Halliday, Ian, Perrault, Cecile, Gunn, Julian, Evans, Paul C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157135/ https://www.ncbi.nlm.nih.gov/pubmed/27671802 http://dx.doi.org/10.1093/cvr/cvw210 |
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