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Dendrobium alkaloids prevent Aβ(25–35)-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice

BACKGROUND: Neuronal and synaptic loss is the most important risk factor for cognitive impairment. Inhibiting neuronal apoptosis and preventing synaptic loss are promising therapeutic approaches for Alzheimer’s disease (AD). In this study, we investigate the protective effects of Dendrobium alkaloid...

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Detalles Bibliográficos
Autores principales: Nie, Jing, Tian, Yong, Zhang, Yu, Lu, Yan-Liu, Li, Li-Sheng, Shi, Jing-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157189/
https://www.ncbi.nlm.nih.gov/pubmed/27994964
http://dx.doi.org/10.7717/peerj.2739