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Dendrobium alkaloids prevent Aβ(25–35)-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice
BACKGROUND: Neuronal and synaptic loss is the most important risk factor for cognitive impairment. Inhibiting neuronal apoptosis and preventing synaptic loss are promising therapeutic approaches for Alzheimer’s disease (AD). In this study, we investigate the protective effects of Dendrobium alkaloid...
Autores principales: | Nie, Jing, Tian, Yong, Zhang, Yu, Lu, Yan-Liu, Li, Li-Sheng, Shi, Jing-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157189/ https://www.ncbi.nlm.nih.gov/pubmed/27994964 http://dx.doi.org/10.7717/peerj.2739 |
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