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Lymph node biopsy analysis reveals an altered immunoregulatory balance already during the at‐risk phase of autoantibody positive rheumatoid arthritis

The balance between proinflammatory and regulatory CD4(+) T cells is tightly controlled in lymphoid organs. In autoimmune diseases this balance is altered in the periphery and target tissue of patients. However, not much is known about the balance initiated in lymphoid organs during the development...

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Detalles Bibliográficos
Autores principales: Ramwadhdoebe, Tamara H., Hähnlein, Janine, Maijer, Karen I., van Boven, Leonard J., Gerlag, Danielle M., Tak, Paul P., van Baarsen, Lisa G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157721/
https://www.ncbi.nlm.nih.gov/pubmed/27645315
http://dx.doi.org/10.1002/eji.201646393