Hydrogen peroxide‐mediated conversion of coproheme to heme b by HemQ—lessons from the first crystal structure and kinetic studies

Heme biosynthesis in Gram‐positive bacteria follows a recently described coproporphyrin‐dependent pathway with HemQ catalyzing the decarboxylation of coproheme to heme b. Here we present the first crystal structure of a HemQ (homopentameric coproheme‐HemQ from Listeria monocytogenes) at 1.69 Å resol...

Descripción completa

Detalles Bibliográficos
Autores principales: Hofbauer, Stefan, Mlynek, Georg, Milazzo, Lisa, Pühringer, Dominic, Maresch, Daniel, Schaffner, Irene, Furtmüller, Paul G., Smulevich, Giulietta, Djinović‐Carugo, Kristina, Obinger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157759/
https://www.ncbi.nlm.nih.gov/pubmed/27758026
http://dx.doi.org/10.1111/febs.13930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157759/
https://www.ncbi.nlm.nih.gov/pubmed/27758026
http://dx.doi.org/10.1111/febs.13930

Ejemplares similares