Crystal structure of a peptidyl‐dipeptidase K‐26‐DCP from Actinomycete in complex with its natural inhibitor

Several soil‐derived Actinobacteria produce secondary metabolites that are proven specific and potent inhibitors of the human angiotensin‐I‐converting enzyme (ACE), a key target for the modulation of hypertension through its role in the renin–angiotensin–aldosterone system. K‐26‐DCP is a zinc dipept...

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Detalles Bibliográficos
Autores principales: Masuyer, Geoffrey, Cozier, Gyles E., Kramer, Glenna J., Bachmann, Brian O., Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157764/
https://www.ncbi.nlm.nih.gov/pubmed/27754586
http://dx.doi.org/10.1111/febs.13928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157764/
https://www.ncbi.nlm.nih.gov/pubmed/27754586
http://dx.doi.org/10.1111/febs.13928

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