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Multi‐arm group sequential designs with a simultaneous stopping rule

Multi‐arm group sequential clinical trials are efficient designs to compare multiple treatments to a control. They allow one to test for treatment effects already in interim analyses and can have a lower average sample number than fixed sample designs. Their operating characteristics depend on the s...

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Detalles Bibliográficos
Autores principales: Urach, S., Posch, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157767/
https://www.ncbi.nlm.nih.gov/pubmed/27550822
http://dx.doi.org/10.1002/sim.7077