Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome

Bloom syndrome is a recessive human genetic disorder with features of genome instability, growth deficiency and predisposition to cancer. The only known causative gene is the BLM helicase that is a member of a protein complex along with topoisomerase III alpha, RMI1 and 2, which maintains replicatio...

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Detalles Bibliográficos
Autores principales: Hudson, Damien F., Amor, David J., Boys, Amber, Butler, Kathy, Williams, Lorna, Zhang, Tao, Kalitsis, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157948/
https://www.ncbi.nlm.nih.gov/pubmed/27977684
http://dx.doi.org/10.1371/journal.pgen.1006483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157948/
https://www.ncbi.nlm.nih.gov/pubmed/27977684
http://dx.doi.org/10.1371/journal.pgen.1006483

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