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Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome
Bloom syndrome is a recessive human genetic disorder with features of genome instability, growth deficiency and predisposition to cancer. The only known causative gene is the BLM helicase that is a member of a protein complex along with topoisomerase III alpha, RMI1 and 2, which maintains replicatio...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157948/ https://www.ncbi.nlm.nih.gov/pubmed/27977684 http://dx.doi.org/10.1371/journal.pgen.1006483 |