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Mutation Rate Variation is a Primary Determinant of the Distribution of Allele Frequencies in Humans
The site frequency spectrum (SFS) has long been used to study demographic history and natural selection. Here, we extend this summary by examining the SFS conditional on the alleles found at the same site in other species. We refer to this extension as the “phylogenetically-conditioned SFS” or cSFS....
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157949/ https://www.ncbi.nlm.nih.gov/pubmed/27977673 http://dx.doi.org/10.1371/journal.pgen.1006489 |