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Universal or Specific? A Modeling-Based Comparison of Broad-Spectrum Influenza Vaccines against Conventional, Strain-Matched Vaccines

Despite the availability of vaccines, influenza remains a major public health challenge. A key reason is the virus capacity for immune escape: ongoing evolution allows the continual circulation of seasonal influenza, while novel influenza viruses invade the human population to cause a pandemic every...

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Detalles Bibliográficos
Autores principales: Subramanian, Rahul, Graham, Andrea L., Grenfell, Bryan T., Arinaminpathy, Nimalan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157952/
https://www.ncbi.nlm.nih.gov/pubmed/27977667
http://dx.doi.org/10.1371/journal.pcbi.1005204