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Characterization of Histone Modifications Associated with Inactive X-Chromosome in Trophoblast Stem Cells, eXtra-Embryonic Endoderm Cells and in In Vitro Derived Undifferentiated and Differentiated Epiblast Like Stem Cells

In mouse, X-chromosome inactivation (XCI) can either be imprinted or random. Imprinted XCI (iXCI) is considered unstable and depending on continuous Xist expression, whereas random XCI (rXCI) is stably maintained even in the absence of Xist. Here we have systematically examined epigenetic modificati...

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Detalles Bibliográficos
Autores principales: Dupont, Cathérine, Maduro, Cheryl, Den Braanker, Hannah, Boers, Ruben, Kurek, Dorota, Gribnau, Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5157996/
https://www.ncbi.nlm.nih.gov/pubmed/27977710
http://dx.doi.org/10.1371/journal.pone.0167154