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Knockdown of Long Non-Coding RNA UCA1 Increases the Tamoxifen Sensitivity of Breast Cancer Cells through Inhibition of Wnt/β-Catenin Pathway

Acquired resistance to tamoxifen remains a major obstacle in breast cancer (BC) treatment, since the underlying mechanism has not been fully elucidated. The long non-coding RNA (lncRNA) urothelial carcinoma-associated 1 (UCA1) has been recently shown to be dysregulated and plays important roles in p...

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Detalles Bibliográficos
Autores principales: Liu, Hongying, Wang, Gang, Yang, Lili, Qu, Jianjun, Yang, Zhihui, Zhou, Xiangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158064/
https://www.ncbi.nlm.nih.gov/pubmed/27977766
http://dx.doi.org/10.1371/journal.pone.0168406