Exon junction complex proteins bind nascent transcripts independently of pre-mRNA splicing in Drosophila melanogaster

Although it is currently understood that the exon junction complex (EJC) is recruited on spliced mRNA by a specific interaction between its central protein, eIF4AIII, and splicing factor CWC22, we found that eIF4AIII and the other EJC core proteins Y14 and MAGO bind the nascent transcripts of not on...

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Detalles Bibliográficos
Autores principales: Choudhury, Subhendu Roy, Singh, Anand K, McLeod, Tina, Blanchette, Marco, Jang, Boyun, Badenhorst, Paul, Kanhere, Aditi, Brogna, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158136/
https://www.ncbi.nlm.nih.gov/pubmed/27879206
http://dx.doi.org/10.7554/eLife.19881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158136/
https://www.ncbi.nlm.nih.gov/pubmed/27879206
http://dx.doi.org/10.7554/eLife.19881

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