Pertussis Toxin Is a Robust and Selective Inhibitor of High Grade Glioma Cell Migration and Invasion

In high grade glioma (HGG), extensive tumor cell infiltration of normal brain typically precludes identifying effective margins for surgical resection or irradiation. Pertussis toxin (PT) is a multimeric complex that inactivates diverse G(i/o) G-protein coupled receptors (GPCRs). Despite the broad c...

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Detalles Bibliográficos
Autores principales: Gilder, Andrew S., Wang, Lei, Natali, Letizia, Karimi-Mostowfi, Nicki, Brifault, Coralie, Gonias, Steven L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158192/
https://www.ncbi.nlm.nih.gov/pubmed/27977780
http://dx.doi.org/10.1371/journal.pone.0168418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158192/
https://www.ncbi.nlm.nih.gov/pubmed/27977780
http://dx.doi.org/10.1371/journal.pone.0168418

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