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Enhanced Expression of Trib3 during the Development of Myelin Breakdown in dmy Myelin Mutant Rats
The demyelination (dmy) rat exhibits hind limb ataxia and severe myelin breakdown in the central nervous system. The causative gene of dmy rats is the MRS2 magnesium transporter gene. Tribbles homolog 3 (Trib3) is a pseudokinase molecule that modifies certain signal pathways, and its expression is i...
Autores principales: | Shimotsuma, Yukako, Tanaka, Miyuu, Izawa, Takeshi, Yamate, Jyoji, Kuwamura, Mitsuru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158197/ https://www.ncbi.nlm.nih.gov/pubmed/27977799 http://dx.doi.org/10.1371/journal.pone.0168250 |
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