The Proteasome Inhibitor Bortezomib Affects Chondrosarcoma Cells via the Mitochondria-Caspase Dependent Pathway and Enhances Death Receptor Expression and Autophagy

High grade chondrosarcoma is characterized by its lack of response to conventional cytotoxic chemotherapy, the tendency to develop lung metastases, and low survival rates. Research within the field prioritizes the development and expansion of new treatment options for dealing with unresectable or me...

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Detalles Bibliográficos
Autores principales: Lohberger, Birgit, Steinecker-Frohnwieser, Bibiane, Stuendl, Nicole, Kaltenegger, Heike, Leithner, Andreas, Rinner, Beate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158315/
https://www.ncbi.nlm.nih.gov/pubmed/27978543
http://dx.doi.org/10.1371/journal.pone.0168193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5158315/
https://www.ncbi.nlm.nih.gov/pubmed/27978543
http://dx.doi.org/10.1371/journal.pone.0168193

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