Progressive Seizure Aggravation in the Repeated 6-Hz Corneal Stimulation Model Is Accompanied by Marked Increase in Hippocampal p-ERK1/2 Immunoreactivity in Neurons

The 6-Hz corneal stimulation test is used to screen novel antiepileptic molecules to overcome the problem of drug refractoriness. Although recognized as a standard test, it has been evaluated only recently in the attempt to characterize the putative neuronal networks involved in seizures caused by c...

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Detalles Bibliográficos
Autores principales: Giordano, Carmela, Costa, Anna M., Lucchi, Chiara, Leo, Giuseppina, Brunel, Luc, Fehrentz, Jean-Alain, Martinez, Jean, Torsello, Antonio, Biagini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159434/
https://www.ncbi.nlm.nih.gov/pubmed/28018175
http://dx.doi.org/10.3389/fncel.2016.00281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159434/
https://www.ncbi.nlm.nih.gov/pubmed/28018175
http://dx.doi.org/10.3389/fncel.2016.00281

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