A multi-step model for facilitated unwinding of the yeast U4/U6 RNA duplex

The small nuclear RNA (snRNA) components of the spliceosome undergo many conformational rearrangements during its assembly, catalytic activation and disassembly. The U4 and U6 snRNAs are incorporated into the spliceosome as a base-paired complex within the U4/U6.U5 small nuclear ribonucleoprotein (t...

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Detalles Bibliográficos
Autores principales: Rodgers, Margaret L., Didychuk, Allison L., Butcher, Samuel E., Brow, David A., Hoskins, Aaron A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159527/
https://www.ncbi.nlm.nih.gov/pubmed/27484481
http://dx.doi.org/10.1093/nar/gkw686

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159527/
https://www.ncbi.nlm.nih.gov/pubmed/27484481
http://dx.doi.org/10.1093/nar/gkw686

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