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tRNA anticodon loop modifications ensure protein homeostasis and cell morphogenesis in yeast

Using budding yeast, we investigated a negative interaction network among genes for tRNA modifications previously implicated in anticodon-codon interaction: 5-methoxy-carbonyl-methyl-2-thio-uridine (mcm(5)s(2)U34: ELP3, URM1), pseudouridine (Ψ38/39: DEG1) and cyclic N6-threonyl-carbamoyl-adenosine (...

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Detalles Bibliográficos
Autores principales: Klassen, Roland, Ciftci, Akif, Funk, Johanna, Bruch, Alexander, Butter, Falk, Schaffrath, Raffael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159529/
https://www.ncbi.nlm.nih.gov/pubmed/27496282
http://dx.doi.org/10.1093/nar/gkw705