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Personalized characterization of diseases using sample-specific networks

A complex disease generally results not from malfunction of individual molecules but from dysfunction of the relevant system or network, which dynamically changes with time and conditions. Thus, estimating a condition-specific network from a single sample is crucial to elucidating the molecular mech...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoping, Wang, Yuetong, Ji, Hongbin, Aihara, Kazuyuki, Chen, Luonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159538/
https://www.ncbi.nlm.nih.gov/pubmed/27596597
http://dx.doi.org/10.1093/nar/gkw772