A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness

Self-renewal and pluripotency are two fundamental characteristics of embryonic stem cells (ESCs) and are controlled by diverse regulatory factors, including pluripotent factors, epigenetic regulators and microRNAs (miRNAs). Although histone methyltransferases are key epigenetic regulators, whether a...

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Detalles Bibliográficos
Autores principales: Lee, Sung-Hun, Chen, Tsai-Yu, Dhar, Shilpa S., Gu, Bingnan, Chen, Kaifu, Kim, Young Zoon, Li, Wei, Lee, Min Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159542/
https://www.ncbi.nlm.nih.gov/pubmed/27625395
http://dx.doi.org/10.1093/nar/gkw788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159542/
https://www.ncbi.nlm.nih.gov/pubmed/27625395
http://dx.doi.org/10.1093/nar/gkw788

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