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Single-molecule analysis of ϕC31 integrase-mediated site-specific recombination by tethered particle motion

Serine and tyrosine site-specific recombinases (SRs and YRs, respectively) provide templates for understanding the chemical mechanisms and conformational dynamics of strand cleavage/exchange between DNA partners. Current evidence suggests a rather intriguing mechanism for serine recombination, in wh...

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Detalles Bibliográficos
Autores principales: Fan, Hsiu-Fang, Hsieh, Tao-shih, Ma, Chien-Hui, Jayaram, Makkuni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159548/
https://www.ncbi.nlm.nih.gov/pubmed/27986956
http://dx.doi.org/10.1093/nar/gkw861