AKAP12 mediates PKA-induced phosphorylation of ATR to enhance nucleotide excision repair

Loss-of-function in melanocortin 1 receptor (MC1R), a G(S) protein-coupled receptor that regulates signal transduction through cAMP and protein kinase A (PKA) in melanocytes, is a major inherited melanoma risk factor. Herein, we report a novel cAMP-mediated response for sensing and responding to UV-...

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Detalles Bibliográficos
Autores principales: Jarrett, Stuart G., Wolf Horrell, Erin M., D'Orazio, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159552/
https://www.ncbi.nlm.nih.gov/pubmed/27683220
http://dx.doi.org/10.1093/nar/gkw871

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159552/
https://www.ncbi.nlm.nih.gov/pubmed/27683220
http://dx.doi.org/10.1093/nar/gkw871

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