FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end

The FANCI-FANCD2 (I-D) complex is considered to work with RAD51 to protect the damaged DNA in the stalled replication fork. However, the means by which this DNA protection is accomplished have remained elusive. In the present study, we found that the I-D complex directly binds to RAD51, and stabiliz...

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Detalles Bibliográficos
Autores principales: Sato, Koichi, Shimomuki, Mayo, Katsuki, Yoko, Takahashi, Daisuke, Kobayashi, Wataru, Ishiai, Masamichi, Miyoshi, Hiroyuki, Takata, Minoru, Kurumizaka, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159555/
https://www.ncbi.nlm.nih.gov/pubmed/27694619
http://dx.doi.org/10.1093/nar/gkw876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159555/
https://www.ncbi.nlm.nih.gov/pubmed/27694619
http://dx.doi.org/10.1093/nar/gkw876

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