Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction

APRIN (PDS5 cohesin associated factor B) interacts with both the cohesin complex and the BRCA2 tumor suppressor. How APRIN influences cohesion and DNA repair processes is not well understood. Here, we show that APRIN is recruited to DNA damage sites. We find that APRIN interacts directly with RAD51,...

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Detalles Bibliográficos
Autores principales: Couturier, Anthony M., Fleury, Hubert, Patenaude, Anne-Marie, Bentley, Victoria L., Rodrigue, Amélie, Coulombe, Yan, Niraj, Joshi, Pauty, Joris, Berman, Jason N., Dellaire, Graham, Di Noia, Javier M., Mes-Masson, Anne-Marie, Masson, Jean-Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159559/
https://www.ncbi.nlm.nih.gov/pubmed/27924011
http://dx.doi.org/10.1093/nar/gkw921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159559/
https://www.ncbi.nlm.nih.gov/pubmed/27924011
http://dx.doi.org/10.1093/nar/gkw921

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