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Cholinergic Interneurons Amplify Corticostriatal Synaptic Responses in the Q175 Model of Huntington’s Disease
Huntington’s disease (HD) is a neurodegenerative disorder characterized by deficits in movement control that are widely viewed as stemming from pathophysiological changes in the striatum. Giant, aspiny cholinergic interneurons (ChIs) are key elements in the striatal circuitry controlling movement, b...
Autores principales: | Tanimura, Asami, Lim, Sean Austin O., Aceves Buendia, Jose de Jesus, Goldberg, Joshua A., Surmeier, D. James |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159611/ https://www.ncbi.nlm.nih.gov/pubmed/28018188 http://dx.doi.org/10.3389/fnsys.2016.00102 |
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