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Kc167, a widely used Drosophila cell line, contains an active primary piRNA pathway

PIWI family proteins bind to small RNAs known as PIWI-interacting RNAs (piRNAs) and play essential roles in the germline by silencing transposons and by promoting germ cell specification and function. Here we report that the widely used Kc167 cell line, derived from Drosophila melanogaster embryos,...

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Detalles Bibliográficos
Autores principales: Vrettos, Nicholas, Maragkakis, Manolis, Alexiou, Panagiotis, Mourelatos, Zissimos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159643/
https://www.ncbi.nlm.nih.gov/pubmed/27789612
http://dx.doi.org/10.1261/rna.059139.116