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Genome-scale characterization of RNA tertiary structures and their functional impact by RNA solvent accessibility prediction

As most RNA structures are elusive to structure determination, obtaining solvent accessible surface areas (ASAs) of nucleotides in an RNA structure is an important first step to characterize potential functional sites and core structural regions. Here, we developed RNAsnap, the first machine-learnin...

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Detalles Bibliográficos
Autores principales: Yang, Yuedong, Li, Xiaomei, Zhao, Huiying, Zhan, Jian, Wang, Jihua, Zhou, Yaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159645/
https://www.ncbi.nlm.nih.gov/pubmed/27807179
http://dx.doi.org/10.1261/rna.057364.116