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Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex

The exon junction complex (EJC) is a multiprotein complex integral to mRNA metabolism. Biochemistry and genetic studies have concluded that the EJC is composed of four core proteins, MAGOH, EIF4A3, RBM8A, and CASC3. Yet recent studies in Drosophila indicate divergent physiological functions for Bare...

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Detalles Bibliográficos
Autores principales: Mao, Hanqian, Brown, Hannah E., Silver, Debra L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159646/
https://www.ncbi.nlm.nih.gov/pubmed/27780844
http://dx.doi.org/10.1261/rna.058826.116