Cargando…

Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex

The exon junction complex (EJC) is a multiprotein complex integral to mRNA metabolism. Biochemistry and genetic studies have concluded that the EJC is composed of four core proteins, MAGOH, EIF4A3, RBM8A, and CASC3. Yet recent studies in Drosophila indicate divergent physiological functions for Bare...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mao, Hanqian, Brown, Hannah E., Silver, Debra L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159646/ https://www.ncbi.nlm.nih.gov/pubmed/27780844 http://dx.doi.org/10.1261/rna.058826.116

Ejemplares similares

Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly
por: Mao, Hanqian, et al.
Publicado: (2016)

CASC3 promotes transcriptome-wide activation of nonsense-mediated decay by the exon junction complex
por: Gerbracht, Jennifer V, et al.
Publicado: (2020)

The exon junction complex component Magoh controls brain size by regulating neural stem cell division
por: Silver, Debra L., et al.
Publicado: (2010)

The Physiological Roles of the Exon Junction Complex in Development and Diseases
por: Asthana, Shravan, et al.
Publicado: (2022)

Putatively cancer-specific exon–exon junctions are shared across patients and present in developmental and other non-cancer cells
por: David, Julianne K, et al.
Publicado: (2020)

Exon junction complex (EJC) core genes play multiple developmental roles in Physalis floridana
por: Gong, Pichang, et al.
Publicado: (2018)

Exon Junction Complexes can have distinct functional flavours to regulate specific splicing events
por: Wang, Zhen, et al.
Publicado: (2018)

TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR
por: Fiesel, Fabienne C., et al.
Publicado: (2012)

A Day in the Life of the Exon Junction Complex
por: Schlautmann, Lena P., et al.
Publicado: (2020)

The RNA-binding profile of Acinus, a peripheral component of the exon junction complex, reveals its role in splicing regulation
por: Rodor, Julie, et al.
Publicado: (2016)

Exon junction complex components Y14 and Mago still play a role in budding yeast
por: Boisramé, Anita, et al.
Publicado: (2019)

Transcriptome-wide modulation of splicing by the exon junction complex
por: Wang, Zhen, et al.
Publicado: (2014)

JuncDB: an exon–exon junction database
por: Chorev, Michal, et al.
Publicado: (2016)

An innovative CASC training redesign – ‘experience of virtual mock CASC exam’
por: Rankin, Jennifer, et al.
Publicado: (2021)

Perispeckles are major assembly sites for the exon junction core complex
por: Daguenet, Elisabeth, et al.
Publicado: (2012)

Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing
por: Blazquez, Lorea, et al.
Publicado: (2018)

Exon junction complex shapes the m(6)A epitranscriptome
por: Yang, Xin, et al.
Publicado: (2022)

Diverse Roles of the Exon Junction Complex Factors in the Cell Cycle, Cancer, and Neurodevelopmental Disorders-Potential for Therapeutic Targeting
por: Martin, Hannah, et al.
Publicado: (2022)

The exon junction complex is required for definition and excision of neighboring introns in Drosophila
por: Hayashi, Rippei, et al.
Publicado: (2014)

Function and Pathological Implications of Exon Junction Complex Factor Y14
por: Chuang, Tzu-Wei, et al.
Publicado: (2015)

Promoter-proximal pausing mediated by the exon junction complex regulates splicing
por: Akhtar, Junaid, et al.
Publicado: (2019)

The exon junction complex is required for stem and progenitor cell maintenance in planarians
por: Kimball, Casey, et al.
Publicado: (2019)

A national CASC course
por: Ramesh, Yathooshan, et al.
Publicado: (2021)

Full function of exon junction complex factor, Rbm8a, is critical for interneuron development
por: McSweeney, Colleen, et al.
Publicado: (2020)

Comprehensive mapping of exon junction complex binding sites reveals universal EJC deposition in Drosophila
por: Morillo, Lucía, et al.
Publicado: (2023)

The abundance of RNPS1, a protein component of the exon junction complex, can determine the variability in efficiency of the Nonsense Mediated Decay pathway
por: Viegas, Marcelo H., et al.
Publicado: (2007)

The Exon Junction Complex and intron removal prevent re-splicing of mRNA
por: Joseph, Brian, et al.
Publicado: (2021)

Exon Junction Complex Is a Molecular Compass of N(6)-Methyladenosine Modification
por: Jung, Inhong, et al.
Publicado: (2023)

In vitro FRAP reveals the ATP-dependent nuclear mobilization of the exon junction complex protein SRm160
por: Wagner, Stefan, et al.
Publicado: (2004)

Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences
por: Su, Wan-Lin, et al.
Publicado: (2008)

Prediction of alternatively skipped exons and splicing enhancers from exon junction arrays
por: Kechris, Katerina, et al.
Publicado: (2008)

Identification of Antiviral Roles for the Exon-Junction Complex and Nonsense-Mediated Decay in Flaviviral Infection
por: Li, Minghua, et al.
Publicado: (2019)

Exon-dependent transcriptional adaptation by exon-junction complex proteins Y14/RNP-4 and MAGOH/MAG-1 in Caenorhabditis elegans
por: Fernandez-Abascal, Jesus, et al.
Publicado: (2022)

The Usage of Exon-Exon Splice Junctions for the Detection of Alternative Splicing using the REIDS model
por: Van Moerbeke, Marijke, et al.
Publicado: (2018)

A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
por: Mo, Fan, et al.
Publicado: (2008)

Computer algebra in scientific computing: CASC 2000
por: Ganzha, Victor, et al.
Publicado: (2000)

Developing a virtual mock casc for trainees
por: Somerville, Laura, et al.
Publicado: (2021)

A review on the role of CASC11 in cancers
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2023)

The exon junction complex controls transposable element activity by ensuring faithful splicing of the piwi transcript
por: Malone, Colin D., et al.
Publicado: (2014)

Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay
por: Singh, Kusum K, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_fqo52r6591kjsko39d04ngjg2v