Cargando…

Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A

Spliceostatin A (SSA) is a methyl ketal derivative of FR901464, a potent antitumor compound isolated from a culture broth of Pseudomonas sp. no. 2663. These compounds selectively bind to the essential spliceosome component SF3b, a subcomplex of the U2 snRNP, to inhibit pre-mRNA splicing. However, th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yoshimoto, Rei, Kaida, Daisuke, Furuno, Masaaki, Burroughs, A. Maxwell, Noma, Shohei, Suzuki, Harukazu, Kawamura, Yumi, Hayashizaki, Yoshihide, Mayeda, Akila, Yoshida, Minoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159648/ https://www.ncbi.nlm.nih.gov/pubmed/27754875 http://dx.doi.org/10.1261/rna.058065.116

Ejemplares similares

Competition between a noncoding exon and introns: Gomafu contains tandem UACUAAC repeats and associates with splicing factor-1
por: Tsuiji, Hitomi, et al.
Publicado: (2011)

CCNE1 and E2F1 Partially Suppress G1 Phase Arrest Caused by Spliceostatin A Treatment
por: Kikuchi, Kei, et al.
Publicado: (2021)

Syntheses of spliceostatins and thailanstatins: a review
por: Donaldson, William A
Publicado: (2020)

Rbm38 Reduces the Transcription Elongation Defect of the SMEK2 Gene Caused by Splicing Deficiency
por: Muraoka, Shintaro, et al.
Publicado: (2020)

Enantioselective Total Syntheses of FR901464 and Spliceostatin A and Evaluation of Splicing Activity of Key Derivatives
por: Ghosh, Arun K., et al.
Publicado: (2014)

Enantioselective Synthesis of Spliceostatin E and Evaluation of Biological Activity
por: Ghosh, Arun K., et al.
Publicado: (2014)

Spliceostatin A inhibits spliceosome assembly subsequent to prespliceosome formation
por: Roybal, Gabriel A., et al.
Publicado: (2010)

SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns
por: Fukumura, Kazuhiro, et al.
Publicado: (2021)

Re-splicing of mature mRNA in cancer cells promotes activation of distant weak alternative splice sites
por: Kameyama, Toshiki, et al.
Publicado: (2012)

Human genome research enters a new phase
por: Suzuki, Harukazu, et al.
Publicado: (2005)

Biosynthesis of Circular RNA ciRS-7/CDR1as Is Mediated by Mammalian-wide Interspersed Repeats
por: Yoshimoto, Rei, et al.
Publicado: (2020)

The Exon Junction Complex Core Represses Cancer-Specific Mature mRNA Re-splicing: A Potential Key Role in Terminating Splicing
por: Otani, Yuta, et al.
Publicado: (2021)

Spliceostatin C, a component of a microbial bioherbicide, is a potent phytotoxin that inhibits the spliceosome
por: Bajsa-Hirschel, Joanna, et al.
Publicado: (2023)

U2 snRNP Is Required for Expression of the 3′ End of Genes
por: Koga, Mitsunori, et al.
Publicado: (2014)

Publisher Correction: Nanopore sequencing reveals TACC2 locus complexity and diversity of isoforms transcribed from an intronic promoter
por: Ito, Yosuke, et al.
Publicado: (2021)

Nanopore sequencing reveals TACC2 locus complexity and diversity of isoforms transcribed from an intronic promoter
por: Ito, Yosuke, et al.
Publicado: (2021)

Clusters of Internally Primed Transcripts Reveal Novel Long Noncoding RNAs
por: Furuno, Masaaki, et al.
Publicado: (2006)

pre-miRNA profiles obtained through application of locked nucleic acids and deep sequencing reveals complex 5′/3′ arm variation including concomitant cleavage and polyuridylation patterns
por: Burroughs, A. Maxwell, et al.
Publicado: (2012)

Two-step cleavage of hairpin RNA with 5' overhangs by human DICER
por: Ando, Yoshinari, et al.
Publicado: (2011)

Cancer-Specifically Re-Spliced TSG101 mRNA Promotes Invasion and Metastasis of Nasopharyngeal Carcinoma
por: Chua, Huey-Huey, et al.
Publicado: (2019)

Epstein-Barr Virus Enhances Cancer-Specific Aberrant Splicing of TSG101 Pre-mRNA
por: Chua, Huey-Huey, et al.
Publicado: (2022)

Complete Genome Sequence of Soil Bacterium Burkholderia sp. Strain FERM BP-3421, a Producer of Spliceostatins
por: Kunakom, Sylvia, et al.
Publicado: (2023)

Beyond the FANTOM4
por: Suzuki, Harukazu, et al.
Publicado: (2010)

Nuclear Pore Complex Protein Mediated Nuclear Localization of Dicer Protein in Human Cells
por: Ando, Yoshinari, et al.
Publicado: (2011)

Characterization of RNase R-digested cellular RNA source that consists of lariat and circular RNAs from pre-mRNA splicing
por: Suzuki, Hitoshi, et al.
Publicado: (2006)

The reciprocal regulation between splicing and 3′‐end processing
por: Kaida, Daisuke
Publicado: (2016)

LOCATE: a mouse protein subcellular localization database
por: Fink, J. Lynn, et al.
Publicado: (2006)

ZNF265—a novel spliceosomal protein able to induce alternative splicing
por: Adams, David J., et al.
Publicado: (2001)

Alternative splicing affects the subcellular localization of Drosha
por: Link, Steffen, et al.
Publicado: (2016)

The Exon Junction Complex Controls the Efficient and Faithful Splicing of a Subset of Transcripts Involved in Mitotic Cell-Cycle Progression
por: Fukumura, Kazuhiro, et al.
Publicado: (2016)

Endogenous Multiple Exon Skipping and Back-Splicing at the DMD Mutation Hotspot
por: Suzuki, Hitoshi, et al.
Publicado: (2016)

Isolation and characterization of post-splicing lariat–intron complexes
por: Yoshimoto, Rei, et al.
Publicado: (2009)

CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes
por: Hasegawa, Yuki, et al.
Publicado: (2014)

CORRIGENDUM: CCL2 enhances pluripotency of human induced pluripotent stem cells by activating hypoxia related genes
por: Hasegawa, Yuki, et al.
Publicado: (2014)

HnRNP L and hnRNP LL antagonistically modulate PTB-mediated splicing suppression of CHRNA1 pre-mRNA
por: Rahman, Mohammad Alinoor, et al.
Publicado: (2013)

Editorial: RNA Diseases in Humans—From Fundamental Research to Therapeutic Applications
por: Kataoka, Naoyuki, et al.
Publicado: (2019)

Development of a high-throughput method for the systematic identification of human proteins nuclear translocation potential
por: Hoat, Trinh Xuan, et al.
Publicado: (2009)

Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD
por: Koga, Mitsunori, et al.
Publicado: (2015)

Identification of the Specific Interactors of the Human Lariat RNA Debranching Enzyme 1 Protein
por: Masaki, So, et al.
Publicado: (2015)

Data-driven normalization strategies for high-throughput quantitative RT-PCR
por: Mar, Jessica C, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_i8kl4dmr8c6ql82sbvmhvpfut4