Alternative splicing of the OCC-1 gene generates three splice variants and a novel exonic microRNA, which regulate the Wnt signaling pathway

The Wnt signaling pathway is hyperactivated in most colorectal cancers (CRC). Finding new regulators of this pathway represents the potential for cancer diagnosis or treatment. OCC-1 was initially reported as an up-regulated gene in colon carcinoma, without knowing its mechanism of action. Here, two...

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Detalles Bibliográficos
Autores principales: Najafi, Hadi, Soltani, Bahram M., Dokanehiifard, Sadat, Nasiri, Shirzad, Mowla, Seyed Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159651/
https://www.ncbi.nlm.nih.gov/pubmed/27986894
http://dx.doi.org/10.1261/rna.056317.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159651/
https://www.ncbi.nlm.nih.gov/pubmed/27986894
http://dx.doi.org/10.1261/rna.056317.116

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