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A PKM generated by calpain cleavage of a classical PKC is required for activity-dependent intermediate-term facilitation in the presynaptic sensory neuron of Aplysia

Atypical PKM, a persistently active form of atypical PKC, is proposed to be a molecular memory trace, but there have been few examinations of the role of PKMs generated from other PKCs. We demonstrate that inhibitors used to inhibit PKMs generated from atypical PKCs are also effective inhibitors of...

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Detalles Bibliográficos
Autores principales: Farah, Carole A., Hastings, Margaret H., Dunn, Tyler W., Gong, Katrina, Baker-Andresen, Danay, Sossin, Wayne S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159657/
https://www.ncbi.nlm.nih.gov/pubmed/27980071
http://dx.doi.org/10.1101/lm.043745.116