IMPs: an RNA-binding protein family that provides a link between stem cell maintenance in normal development and cancer

IMPs, also known as insulin-like growth factor 2 (IGF2) messenger RNA (mRNA)-binding proteins (IGF2BPs), are highly conserved oncofetal RNA-binding proteins (RBPs) that regulate RNA processing at several levels, including localization, translation, and stability. Three mammalian IMP paralogs (IMP1–3...

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Detalles Bibliográficos
Autores principales: Degrauwe, Nils, Suvà, Mario-Luca, Janiszewska, Michalina, Riggi, Nicolo, Stamenkovic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159662/
https://www.ncbi.nlm.nih.gov/pubmed/27940961
http://dx.doi.org/10.1101/gad.287540.116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159662/
https://www.ncbi.nlm.nih.gov/pubmed/27940961
http://dx.doi.org/10.1101/gad.287540.116

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