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Structural visualization of the p53/RNA polymerase II assembly

The master tumor suppressor p53 activates transcription in response to various cellular stresses in part by facilitating recruitment of the transcription machinery to DNA. Recent studies have documented a direct yet poorly characterized interaction between p53 and RNA polymerase II (Pol II). Therefo...

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Detalles Bibliográficos
Autores principales: Singh, Sameer K., Qiao, Zhen, Song, Lihua, Jani, Vijay, Rice, William, Eng, Edward, Coleman, Robert A., Liu, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159667/
https://www.ncbi.nlm.nih.gov/pubmed/27920087
http://dx.doi.org/10.1101/gad.285692.116