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Immune Responses Induced by Recombinant Bacillus Subtilis Expressing the Hemagglutinin Protein of H5N1 in chickens

To develop an effective, safe, and convenient vaccine for the prevention of highly pathogenic avian influenza (HPAI) H5N1, we have constructed a recombinant Bacillus subtilis strain (B.S.-HA) expressing the hemagglutinin (HA) protein. Then we evaluated the immune function in chicken bone marrow deri...

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Detalles Bibliográficos
Autores principales: Mou, Chunxiao, Zhu, Liqi, Yang, Jingjing, Xu, Wenwen, Cheng, Xiaoying, Yang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159790/
https://www.ncbi.nlm.nih.gov/pubmed/27982050
http://dx.doi.org/10.1038/srep38403