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Induction of a Cellular DNA Damage Response by Porcine Circovirus Type 2 Facilitates Viral Replication and Mediates Apoptotic Responses

Cellular DNA damage response (DDR) triggered by infection of DNA viruses mediate cell cycle checkpoint activation, DNA repair, or apoptosis induction. In the present study, infection of porcine circovirus type 2 (PCV2), which serves as a major etiological agent of PCV2-associated diseases (PCVAD), w...

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Detalles Bibliográficos
Autores principales: Wei, Li, Zhu, Shanshan, Wang, Jing, Quan, Rong, Yan, Xu, Li, Zixue, Hou, Lei, Wang, Naidong, Yang, Yi, Jiang, Haijun, Liu, Jue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159794/
https://www.ncbi.nlm.nih.gov/pubmed/27982097
http://dx.doi.org/10.1038/srep39444