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Induction of a Cellular DNA Damage Response by Porcine Circovirus Type 2 Facilitates Viral Replication and Mediates Apoptotic Responses
Cellular DNA damage response (DDR) triggered by infection of DNA viruses mediate cell cycle checkpoint activation, DNA repair, or apoptosis induction. In the present study, infection of porcine circovirus type 2 (PCV2), which serves as a major etiological agent of PCV2-associated diseases (PCVAD), w...
Autores principales: | Wei, Li, Zhu, Shanshan, Wang, Jing, Quan, Rong, Yan, Xu, Li, Zixue, Hou, Lei, Wang, Naidong, Yang, Yi, Jiang, Haijun, Liu, Jue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159794/ https://www.ncbi.nlm.nih.gov/pubmed/27982097 http://dx.doi.org/10.1038/srep39444 |
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