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Phosphorylation of SKAP by GSK3β ensures chromosome segregation by a temporal inhibition of Kif2b activity

Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microtubules. Our recent study shows SKAP is an EB1-dependent, microtubule plus-end tracking protein essential for kinetochore oscillations during mitosis. Here we show that phosphorylat...

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Detalles Bibliográficos
Autores principales: Qin, Bo, Cao, Dan, Wu, Huihui, Mo, Fei, Shao, Hengyi, Chu, Jane, Powell, Michael, Aikhionbare, Felix, Wang, Dongmei, Fu, Chuanhai, He, Ping, Pan, Weijun, Wang, Wenwen, Liu, Xing, Yao, Xuebiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159797/
https://www.ncbi.nlm.nih.gov/pubmed/27982129
http://dx.doi.org/10.1038/srep38791