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Phosphorylation of SKAP by GSK3β ensures chromosome segregation by a temporal inhibition of Kif2b activity
Chromosome segregation in mitosis is orchestrated by the dynamic interactions between the kinetochore and spindle microtubules. Our recent study shows SKAP is an EB1-dependent, microtubule plus-end tracking protein essential for kinetochore oscillations during mitosis. Here we show that phosphorylat...
Autores principales: | Qin, Bo, Cao, Dan, Wu, Huihui, Mo, Fei, Shao, Hengyi, Chu, Jane, Powell, Michael, Aikhionbare, Felix, Wang, Dongmei, Fu, Chuanhai, He, Ping, Pan, Weijun, Wang, Wenwen, Liu, Xing, Yao, Xuebiao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159797/ https://www.ncbi.nlm.nih.gov/pubmed/27982129 http://dx.doi.org/10.1038/srep38791 |
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