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Time Series miRNA-mRNA integrated analysis reveals critical miRNAs and targets in macrophage polarization

Polarization of macrophages is regulated through complex signaling networks. Correlating miRNA and mRNA expression over time after macrophage polarization has not yet been investigated. We used paired RNA-Seq and miRNA-Seq experiments to measure the mRNA and miRNA expression in bone marrow-derived m...

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Detalles Bibliográficos
Autores principales: Lu, Liangqun, McCurdy, Sara, Huang, Sijia, Zhu, Xun, Peplowska, Karolina, Tiirikainen, Maarit, Boisvert, William A., Garmire, Lana X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159803/
https://www.ncbi.nlm.nih.gov/pubmed/27981970
http://dx.doi.org/10.1038/srep37446