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Comprehensive phenotypic analysis of knockout mice deficient in cyclin G1 and cyclin G2

Cyclin G1 (CycG1) and Cyclin G2 (CycG2) play similar roles during the DNA damage response (DDR), but their detailed roles remain elusive. To investigate their distinct roles, we generated knockout mice deficient in CycG1 (G1KO) or CycG2 (G2KO), as well as double knockout mice (DKO) deficient in both...

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Detalles Bibliográficos
Autores principales: Ohno, Shouichi, Ikeda, Jun-ichiro, Naito, Yoko, Okuzaki, Daisuke, Sasakura, Towa, Fukushima, Kohshiro, Nishikawa, Yukihiro, Ota, Kaori, Kato, Yorika, Wang, Mian, Torigata, Kosuke, Kasama, Takashi, Uchihashi, Toshihiro, Miura, Daisaku, Yabuta, Norikazu, Morii, Eiichi, Nojima, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159814/
https://www.ncbi.nlm.nih.gov/pubmed/27982046
http://dx.doi.org/10.1038/srep39091