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A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads

Mechanosensitive biological nanomachines such as motor proteins and ion channels regulate diverse cellular behaviour. Combined optical trapping with single-molecule fluorescence imaging provides a powerful methodology to clearly characterize the mechanoresponse, structural dynamics and stability of...

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Detalles Bibliográficos
Autores principales: Iwaki, M., Wickham, S. F., Ikezaki, K., Yanagida, T., Shih, W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159853/
https://www.ncbi.nlm.nih.gov/pubmed/27941751
http://dx.doi.org/10.1038/ncomms13715