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A programmable DNA origami nanospring that reveals force-induced adjacent binding of myosin VI heads
Mechanosensitive biological nanomachines such as motor proteins and ion channels regulate diverse cellular behaviour. Combined optical trapping with single-molecule fluorescence imaging provides a powerful methodology to clearly characterize the mechanoresponse, structural dynamics and stability of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159853/ https://www.ncbi.nlm.nih.gov/pubmed/27941751 http://dx.doi.org/10.1038/ncomms13715 |