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Pharmacological and genetic reappraisals of protease and oxidative stress pathways in a mouse model of obstructive lung diseases

Protease-antiprotease imbalance and oxidative stress are considered to be major pathophysiological hallmarks of severe obstructive lung diseases including chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF), but limited information is available on their direct roles in the regulati...

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Detalles Bibliográficos
Autores principales: Shuto, Tsuyoshi, Kamei, Shunsuke, Nohara, Hirofumi, Fujikawa, Haruka, Tasaki, Yukihiro, Sugahara, Takuya, Ono, Tomomi, Matsumoto, Chizuru, Sakaguchi, Yuki, Maruta, Kasumi, Nakashima, Ryunosuke, Kawakami, Taisei, Suico, Mary Ann, Kondo, Yoshitaka, Ishigami, Akihito, Takeo, Toru, Tanaka, Ken-ichiro, Watanabe, Hiroshi, Nakagata, Naomi, Uchimura, Kohei, Kitamura, Kenichiro, Li, Jian-Dong, Kai, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159865/
https://www.ncbi.nlm.nih.gov/pubmed/27982104
http://dx.doi.org/10.1038/srep39305