A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors

An enormous amount of tumor sequencing data has been generated through large scale sequencing efforts. The functional consequences of the majority of mutations identified by such projects remain an open, unexplored question. This problem is particularly complicated in the case of rare mutations wher...

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Detalles Bibliográficos
Autores principales: Katigbak, Alexandra, Cencic, Regina, Robert, Francis, Sénécha, Patrick, Scuoppo, Claudio, Pelletier, Jerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159885/
https://www.ncbi.nlm.nih.gov/pubmed/27982060
http://dx.doi.org/10.1038/srep38968

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159885/
https://www.ncbi.nlm.nih.gov/pubmed/27982060
http://dx.doi.org/10.1038/srep38968

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