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A CRISPR/Cas9 Functional Screen Identifies Rare Tumor Suppressors
An enormous amount of tumor sequencing data has been generated through large scale sequencing efforts. The functional consequences of the majority of mutations identified by such projects remain an open, unexplored question. This problem is particularly complicated in the case of rare mutations wher...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159885/ https://www.ncbi.nlm.nih.gov/pubmed/27982060 http://dx.doi.org/10.1038/srep38968 |