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In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway
HIV-1 virions assemble as immature particles containing Gag polyproteins that are processed by the viral protease into individual components, resulting in the formation of mature infectious particles. There are two competing models for the process of forming the mature HIV-1 core: the disassembly an...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159922/ https://www.ncbi.nlm.nih.gov/pubmed/27958264 http://dx.doi.org/10.1038/ncomms13689 |