In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway

HIV-1 virions assemble as immature particles containing Gag polyproteins that are processed by the viral protease into individual components, resulting in the formation of mature infectious particles. There are two competing models for the process of forming the mature HIV-1 core: the disassembly an...

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Detalles Bibliográficos
Autores principales: Ning, Jiying, Erdemci-Tandogan, Gonca, Yufenyuy, Ernest L., Wagner, Jef, Himes, Benjamin A., Zhao, Gongpu, Aiken, Christopher, Zandi, Roya, Zhang, Peijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159922/
https://www.ncbi.nlm.nih.gov/pubmed/27958264
http://dx.doi.org/10.1038/ncomms13689

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